Glossary · Labelling & formulation

pH

What it means

A measure of acidity or alkalinity on a scale of 0 to 14. The skin surface is mildly acidic, typically around pH 4.5 to 5.5. Formula pH affects stability, preservative performance, skin tolerance and how well some actives work: L-ascorbic acid and alpha hydroxy acids, for example, are more effective at low pH.

Sources: 12

Why it matters

Getting this right early shapes the formula, the label and the claims, and avoids costly reformulation once a product is close to launch.

How Guires CSL applies it

Guires CSL formulation, testing, clinical and regulatory teams work with pH on client projects every week, from the first brief to the final product file.

Formulation

References

  1. Peer-reviewed Lambers H, Piessens S, Bloem A, Pronk H, Finkel P. Natural skin surface pH is on average below 5, which is beneficial for its resident flora. Int J Cosmet Sci. 2006;28(5):359-370. pubmed.ncbi.nlm.nih.gov
  2. Peer-reviewed Kornhauser A, Coelho SG, Hearing VJ. Applications of hydroxy acids: classification, mechanisms, and photoactivity. Clin Cosmet Investig Dermatol. 2010;3:135-142. pubmed.ncbi.nlm.nih.gov

Regulations and standards are listed first, then peer-reviewed literature. Sources checked October 2026.

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