CSL Cosmetic Bioscience: a CSL scientist examining samples under the microscope at the Guires R&D Innovation Centre

Cosmetic Bioscience

Cosmetic science, proven in our own lab.

CSL scientists run biotech, cell biology, microbiology, DNA and analytical work at the Guires R&D Innovation Centre in Chennai, so ingredients and claims are tested before they reach your formula.

Guires Cosmetic Science Lab

Cosmetic Bioscience Services from Guires CSL

At Guires Cosmetic Science Lab, CSL scientists offer cosmetic bioscience services from the Guires R&D Innovation Centre in Chennai: biotech and fermented actives, in vitro efficacy testing, animal-free safety screening, microbiology and microbiome testing, halal DNA testing, analytical QC and botanical extracts, with regulatory-grade studies arranged where needed. Skin irritation is screened on reconstructed human epidermis models, the animal-free approach set out in OECD Test Guideline 439.

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Who it is for

Built for brands and ingredient makers.

Beauty brands

Choose actives with lab data behind them, screen formulas early and back claims with mechanism data.

Ingredient suppliers

Develop and scale biotech actives, and build efficacy and safety dossiers for new ingredients.

Contract manufacturers

Microbiology, raw material checks and stability support for your production.

Halal and natural brands

DNA proof for halal and botanical claims, and standardised extracts.

Equipment

Inside the Guires R&D Innovation Centre.

A selection of the instruments CSL scientists use for bioscience, analytical and pilot-scale work.

Cell and molecular biology

  • Cell culture facility
  • CO₂ incubator
  • Biosafety cabinet
  • Laminar air flow
  • Inverted microscope
  • Fluorescence microscope
  • Flow cytometer
  • Microplate reader
  • Real-time PCR
  • Thermal cycler
  • Genetic analyser
  • Electroporator
  • Hybridisation oven

Protein and gel analysis

  • Mini and maxi horizontal gel electrophoresis
  • Mini and maxi vertical gel electrophoresis
  • First- and second-dimension (2D) electrophoresis
  • Semi-dry transfer unit
  • Gel documentation systems (basic and advanced)

Bioprocess and fermentation

  • Fermentors: 5 L, 40 L and 100 L
  • Tangential flow filtration (lab and pilot scale)
  • Continuous high-throughput centrifuge
  • Ultracentrifuge
  • Large, medium and low volume centrifuges
  • Table-top centrifuges
  • Homogeniser and cell disrupter
  • Sonicator
  • Peristaltic pumps

Purification and analytical

  • UPLC
  • FPLC
  • Chromatography system
  • MALDI-TOF/TOF mass spectrometer
  • UV-Vis spectrophotometer
  • Particle size analyser and cell counter
  • pH meter
  • Analytical balances

Concentration and drying

  • Lyophiliser (freeze dryer)
  • Speed vac concentrator
  • Rotary evaporator
  • Vacuum pump
  • Hot air oven

Incubation, storage and utilities

  • BOD incubators
  • Incubator and shaker incubators
  • Temperature-controlled, orbital and water-bath shakers
  • Water baths and heating bath shaker
  • Cold room
  • −80 °C and −20 °C freezers
  • Cryocan (liquid nitrogen storage)
  • Vertical and horizontal autoclaves
  • Purified water system
  • Magnetic and hot-plate stirrers, vortex mixers
  • Ice flaker

Results from the Guires R&D Innovation Centre support formulation decisions, ingredient selection and claims development. Where a market or retailer needs regulatory-grade data, such as GLP safety studies or accredited test reports, CSL arranges those studies as part of the project.

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Start a project

Create your next product with CSL.

Our formulation chemists, testing scientists and regulatory specialists work alongside your team, from the first brief to a market-ready product. Bring a brief, a benchmark or just an idea: a scientist will reply within one working day with next steps and an indicative scope.

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