Glossary · Clinical

SPF (Sun Protection Factor)

What it means

A measure of protection against the UVB rays that cause sunburn. It is traditionally measured on volunteers to ISO 24444; ISO 23675 and ISO 23698 add newer methods for determining SPF without sunburning volunteers.

Sources: 12345

Why it matters

Clinical and instrumental data turn a marketing promise into a claim you can defend with regulators, retailers and consumers.

How Guires CSL applies it

Guires CSL formulation, testing, clinical and regulatory teams work with SPF on client projects every week, from the first brief to the final product file.

Sun protection

References

  1. Regulation Commission Recommendation 2006/647/EC of 22 September 2006 on the efficacy of sunscreen products and the claims made relating thereto. OJ L 265, 26.9.2006, p. 39. eur-lex.europa.eu
  2. Standard ISO 24444:2019 (Amd 1:2022). Cosmetics — Sun protection test methods — In vivo determination of the sun protection factor (SPF). www.iso.org
  3. Standard ISO 23675:2024. Cosmetics — Sun protection test methods — In vitro determination of sun protection factor (SPF). www.iso.org
  4. Standard ISO 23698:2024. Cosmetics — Measurement of the sunscreen efficacy by diffuse reflectance spectroscopy. www.iso.org
  5. Peer-reviewed Pouradier F, et al. Performance assessment of the Double Plate method (ISO 23675) in ALT-SPF Consortium: a highly reproducible and accurate in vitro method to determine SPF. Int J Cosmet Sci. 2025. pubmed.ncbi.nlm.nih.gov

Regulations and standards are listed first, then peer-reviewed literature. Sources checked October 2026.

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