CSL analytical testing: CSL scientists analysing cosmetic samples at the lab bench

Bioscience · Analytical

Measure what matters, batch after batch.

CSL scientists measure actives, preservatives, peptides and particle size at the Guires R&D Innovation Centre, to confirm raw materials, track stability and prove a product contains what the label says.

Guires Cosmetic Science Lab

Cosmetic Analytical Testing from Guires CSL

At Guires Cosmetic Science Lab, CSL scientists provide cosmetic analytical testing at the Guires R&D Innovation Centre: UPLC assays of actives and preservatives, stability monitoring, peptide identity by MALDI-TOF, particle size analysis including nano mineral UV filters, and enzyme activity testing.

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What's included

The work, in detail.

Active and preservative assays

UPLC measurement of actives such as niacinamide, vitamin C and caffeine, and of preservatives, in raw materials and finished products.

UPLC

Stability monitoring

Actives measured over time in accelerated, freeze-thaw and cycling stability studies, alongside pH and appearance.

StabilityShelf life

Peptide and protein identity

Identity and purity of peptides, proteins and enzymes by MALDI-TOF mass spectrometry and gel electrophoresis.

MALDI-TOFSDS-PAGE2D gels

Particle and droplet size

Particle size of pigments and mineral UV filters, including nano-scale zinc oxide and titanium dioxide, and droplet size in emulsions.

Particle sizeNano

Enzyme activity

Activity of enzyme actives such as papain, so products are bought and dosed on real activity.

Activity units

Incoming raw material QC

Raw materials checked against their specification before use, linked to CSL sourcing.

SpecificationCoA check

Deliverables

What you receive.

Analytical reportMethod, results and specification check
Stability dataActive levels over time
SpecificationLimits for release and supplier approval

How it runs

Step by step.

  1. SampleMaterial or product received
  2. MethodMethod selected or developed
  3. AnalyseTesting with controls and standards
  4. ReportResults against specification

Results from the Guires R&D Innovation Centre support formulation decisions, ingredient selection and claims development. Where a market or retailer needs regulatory-grade data, such as GLP safety studies or accredited test reports, CSL arranges those studies as part of the project.

Questions

Asked before we start.

Can you develop a method for a new active?

Yes. CSL scientists develop and check UPLC methods for new actives, which can then be used for release and stability testing.

Can you test for heavy metals or fragrance allergens?

Yes. Heavy metals are measured by ICP-MS, and fragrance allergens by GC-MS, including headspace (HS-GC-MS) and SPME-GC-MS.

Can you confirm a nano claim?

Particle size analysis shows whether a material falls in the nano range. The EU nanomaterial rules also need specific data, which CSL regulatory specialists help compile.

Start a project

Create your next product with CSL.

Our formulation chemists, testing scientists and regulatory specialists work alongside your team, from the first brief to a market-ready product. Bring a brief, a benchmark or just an idea: a scientist will reply within one working day with next steps and an indicative scope.

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